Soft-tissue Fillers for Wrinkles
Soft-tissue fillers (commercially known as Belotero, Juvederm, Radiesse, Restylane, Sculptra and Voluma) contain some form of hyaluronic acid, a substance that naturally occurs throughout the body, with the highest concentrations in the fluids of the eyes and joints. Collagen, once the most common substance used in soft-tissue fillers, is rarely used today. The effect typically lasts about six to 24 months. After that, additional injections are required to maintain the effect.